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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
5.45
Human Site:
T274
Identified Species:
8.57
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
T274
S
W
E
P
N
S
Q
T
K
R
Y
S
G
N
M
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
T274
S
W
E
P
N
S
Q
T
K
R
Y
S
G
N
M
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
Y26
E
Y
I
S
K
M
G
Y
L
D
P
R
N
E
Q
Dog
Lupus familis
XP_534537
1097
121903
P261
G
P
G
G
Q
A
L
P
L
Q
G
P
H
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
Q273
P
S
W
E
P
S
S
Q
T
K
R
Y
S
G
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
M265
T
K
R
Y
S
G
S
M
E
Y
M
I
S
R
I
Chicken
Gallus gallus
XP_419666
1136
127431
Y280
P
N
G
Q
T
K
R
Y
S
G
N
M
E
Y
V
Frog
Xenopus laevis
NP_001087838
1118
125984
E269
T
P
P
P
S
S
W
E
P
G
S
Q
P
K
R
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
G260
R
I
S
P
V
P
Q
G
P
R
G
D
G
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Q263
N
P
Q
Q
Q
L
T
Q
Q
L
K
S
L
N
L
Honey Bee
Apis mellifera
XP_395146
1137
124999
P310
S
N
T
Q
V
E
P
P
P
P
Y
P
I
V
S
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
Q350
A
Q
G
Q
S
I
P
Q
S
N
G
Y
D
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Red Bread Mold
Neurospora crassa
P38679
598
67999
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
0
0
N.A.
6.6
N.A.
N.A.
0
0
13.3
26.6
N.A.
13.3
13.3
0
0
P-Site Similarity:
100
100
6.6
13.3
N.A.
13.3
N.A.
N.A.
26.6
13.3
26.6
33.3
N.A.
40
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% D
% Glu:
7
0
14
7
0
7
0
7
7
0
0
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
20
7
0
7
7
7
0
14
20
0
20
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
7
0
0
7
0
0
0
0
0
7
7
0
14
% I
% Lys:
0
7
0
0
7
7
0
0
14
7
7
0
0
7
0
% K
% Leu:
0
0
0
0
0
7
7
0
14
7
0
0
7
7
7
% L
% Met:
0
0
0
0
0
7
0
7
0
0
7
7
0
0
14
% M
% Asn:
7
14
0
0
14
0
0
0
0
7
7
0
7
20
7
% N
% Pro:
14
20
7
27
7
7
14
14
20
7
7
14
7
0
0
% P
% Gln:
0
7
7
27
14
0
20
20
7
7
0
7
0
0
7
% Q
% Arg:
7
0
7
0
0
0
7
0
0
20
7
7
0
7
14
% R
% Ser:
20
7
7
7
20
27
14
0
14
0
7
20
14
0
7
% S
% Thr:
14
0
7
0
7
0
7
14
7
0
0
0
0
0
0
% T
% Val:
0
0
0
0
14
0
0
0
0
0
0
0
0
7
7
% V
% Trp:
0
14
7
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
14
0
7
20
14
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _